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GR4
Yale University
Autophagy, Neurodegenerative Disease

Gianna discovered her passion for neurobiology as an Undergraduate at Yale University. She graduated with a B.S. in Intensive Molecular, Cellular, and Developmental Biology in 2014, after which she matriculated to the UCI MSTP. She studies the role of autophagy in neurodegenerative disease pathogenesis.

Mineur, Y., Obayemi, A., Wigestrand, M., Fote, G., Calarco, C., Li, A., & Picciotto, M., (n.d.) Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety-and depression-like behavior. (2013). Proceedings of the National Academy of Science, 110(9), 3573-8.
Mineur, Y., Fote, G., Blakeman, S., Cahuzac, E., Newbold, S., Picciotto, M., Multiple nicotinic acetylcholine receptor subtypes in the mouse amygdala regulate effective behaviors and response to social stress. (2016). Neuropsychopharmacology, 41(6), 1579-87.
Marsh, S., Abud, E., Lakatos, A., Yeung, S., Davtyan, H., Fote, G., Lau, L., Weinger, J., Lane, T., Poon, W., Blurton-Jones, M. The Adaptive Immune System Restrains Alzheimer’s Disease Pathogenesis by Modulating Microglial Function. (2015). Proceedings of the National Academy of Science,113(9), 1316-25.
Abud, E. M., Ramirez, R. N., Martinez, E. S., Healy, L. M., Nguyen, C. H. H., Newman, S. A., Yeromin A. V., Scarfone V. M., Marsh S. E., Fimbres C., Caraway C. A., Fote G. M... Blurton-Jones, M. (2017). iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron, 94(2). https://doi.org/10.1016/j.neuron.2017.03.042

2013: Poster, Society for Neuroscience: Cholinergic regulation of hippocampus- amygdala axis in depression-like and stress-related behavior.
2014: Oral Presentation, Columbia Undergraduate Scientific Research Symposium: Mood Regulation by Region-Specific Cholinergic Signaling
2016: Poster, American Physician Scientist Association West Regional Conference:
2016: CD33 SNPs associated with altered gene expression and phagocytosis in PBMCs.
2016: Society for Neuroscience: November 13, 2016.
2016: Poster, Hereditary Disease Foundation Symposium: IKKB slows Huntington’s disease progression in R6/1 mice
2017: Poster, Gordon Research Seminar and Conference, CAG Triplet Repeat Disorders: IKKB slows Huntington’s disease progression in R6/1 mice.
2017: Keystone Symposium Autophagy Network Integration in Health and Disease
2017: Oral Presentation, American Physician Scientist Association Western Regional Conference: Analysis of the interaction between Huntingtin and Ubiquitin
2018: Oral Presentation, Poster, Gordon Research Conference, Autophagy: IKKB slows Huntington’s disease progression in R6/1 mice.