Born and raised in Ohio, Ethan attended Miami University, majoring in zoology and neuroscience. Post-graduation, he continued to work in the lab of Dr. Jaime Imitola at The Ohio State University where he studied how maternal infection alters human brain development using organoids. His doctoral thesis focuses on understanding how noncoding DNA mutations cause disease, like polydactyly and neurodevelopmental disorders, in Dr. Evgeny Kvon's lab.
Hollingsworth EW, Vaughn JE, Orack JC, Skinner CS, Khouri J, Lizarraga SB, Hester ME, Watanabe F, Kosik KS, Imitola J. iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases. EMBO Mol Med. 2017; 9(12):1742-62 (cover article).
Kochli DE, Campbell TL, Hollingsworth EW, Lab RS, Postle AF, Perry MM, Mordzinski VM, Quinn JJ. Combined administration of MK-801 and cycloheximide produces a delayed potentiation of fear discrimination memory extinction. Behav Neurosci. 2018;132(2):99-105.
Coven SL, Stanek JR, Hollingsworth E, Finlay JL. Delays in diagnosis for children with newly diagnosed central nervous system tumors. Neuro-Oncol Pract. 2018 npy002.
Fair SR, Julian D, Pusuluri ST, Malik G, Summerfield T, Zhao G, Hester AB, Ackerman WE, Hollingsworth, EW, Mehboob A, McElroy CA, Buhimschi IA, Imitola J, Maitre NL, Bedrosian TA, Hester ME. Developmental Trajectories of Electrical Properties Reveal Dynamic Neuronal Network Activity in Cerebral Organoids. Stem Cell Rep. In press.
Hollingsworth E, Khouri J, Imitola J. Endogenous repair and development inspired therapy of neurodegeneration in progressive multiple sclerosis. Expert Rev Neurother. 2017; 17(6):611-29.
Julian K, Yuhasz N, Hollingsworth E, Imitola J. The "Growing" Reality of the Neurological Complications of Global "Stem Cell Tourism". Semin Neurol. 2018; 38(2):176-181.
Julian D, Hollingsworth EW, Julian K, Imitola J. Convergence of human cellular models and genetics to study neural stem cell signaling to enhance central nervous system regeneration and repair. Semin Cell Dev Biol. 2019.
T32 NIH Training Program in Stem Cell Translational Medicine for Neurological Disorders, NINDS