MSTP Director | Alan L. Goldin, MD, PhD
Dr. Goldin received his MD,PhD from the University of Michigan and he completed postdoctoral training in molecular neurobiology at Caltech. He is a faculty member in the departments of Microbiology & Molecular Genetics, Anatomy & Neurobiology, and Physiology & Biophysics and he serves as Associate Vice Chancellor for Academic Affairs in the College of Health Sciences. His lab investigates how mutations in ion channel genes cause epilepsy using mouse models and human neurons. Dr. Goldin's goal for the program is to have students with diverse backgrounds and research interests help each other learn to apply rigorous scientific approaches from many fields to research and clinical practice.
A Southern California native, Dr. Monuki received his B.S. in Biology from M.I.T. He then earned his MD,PhD at UC San Diego, after which he completed his Anatomic Pathology and Neuropathology residency and clinical fellowship at Massachusetts Gen, Brigham and Women’s, and Children’s Hospital in Boston, Massachusetts. Upon completion of his clinical training, Dr. Monuki became an attending at the Brigham and Children’s as well as a Howard Hughes postdoctoral fellow at the Beth Israel Deaconess Medical Center. In 2001 he joined UCI’s Department of Pathology, where he studies forebrain development and translational applications using embryonic, induced-pluritpotent, and neural stem cells. He is the Warren L. Bostick Chair of Pathology at UC Irvine. His vision for UCI’s MSTP is to develop new education and training initiatives to prepare the next generation of leaders in academic medicine and to help make our program an MSTP-of-choice for incoming students.
Program Advisors meet with students every quarter and provide guidance regarding selecting a laboratory, research rotations, and more, or direct your questions to someone who can answer them.
Tallie Z. Baram, MD, PhD
Anatomy & Neurbiology
Dr. Baram received her PhD at the Weizmann Institute of Science, Israel, and her MD in the PhD to MD program at the University of Miami, FLA. Baram, a child neurologist and a Neurobiologist is focusing her research on the programming of the developing brain by early-life experience, in two broad contexts: a). how early-life experiences including stress and maternal care influence resilience and vulnerability to cognitive and emotional disorders; b). how early life seizures, especially those associated with fever, can convert a normal brain into an epileptic one. Using rodent models and cutting-edge molecular, cellular epigenetic and imaging methods, Baram’s group is making major contributions to our understanding of the effects of early-life experience on normal brain function and the contributions of early-life adversity and seizures to neuropsychiatric disorders.
Steven Chessler, MD, PhD
Medicine & Endocrinology
Dr. Chessler received his MD, PhD from the University of Washington. He remained at UW to complete a residency in Internal Medicine and a combined research-clinical fellowship in endocrinology, diabetes and metabolism. His laboratory is interested in the biology of the pancreatic islets and in islet failure in diabetes. Current work is focused on the role of extracellular protein interactions in insulin secretion and on identifying candidate cell-surface drug targets for the treatment of diabetes. Dr. Chessler also has a limited clinical practice and participates in the training of medical students, residents and fellows in diabetes and endocrinology.
Robert Edwards, MD, PhD
Pathology & Laboratory
Dr. Edwards received his MD,PhD from Baylor College of Medicine where he also completed a residency in Combined Anatomical and Clinical Pathology. Dr. Edwards completed a Post-Doctoral fellow in Dr. Steven L Kunkel's lab at the University of Michigan. His lab is interested in the relationship between chronic inflammation and colorectal carcinogenesis in human and animal models. Other areas of interest involves include translational research projects performed in collaboration with several clinical investigators at UCI and other institutions . One ongoing project involves a proteomics approach to the serologic diagnosis of IBD and responses to biologic therapies, using patient samples collected at UCIMC.
Anand K Ganesan, MD, PhD
Department of Dermatology
Frithjof Kruggel, MD, PhD
Dr. Kruggel received his M.S. degree in Chemistry and M.D. from Ruhr-University Bochum (Germany, 1983 resp. 1987), and Ph.D. from Ludwig-Maximilian University Munich (Germany, 1989). He completed a residence in Neurology and Clinical Neuropsychology at Kli
nikum rechts der Isar (Munich), after which he joined the Max-Planck-Institute on Cognitive Neuroscience in Leipzig (Germany) as a postdoctoral fellow. In 2005, he joined UCI's Department of Biomedical Engineering, where he studies the relation between structures and functions of the human brain. He is developing and applying new signal and image processing algorithms to the data analysis of neurofunctional methods (anatomical and functional MRI, emission tomography, event-related fields and potentials).
Ulrike Luderer, MD, PhD, MPH
Dr. Luderer received her MD, PhD from Northwestern University and her MPH from the University of Washington. Dr Luderer's research is aimed at elucidating the mechanisms by which toxicants disrupt reproductive function and the protective mechanisms that prevent toxicant-induced reproductive dysfunction. The laboratory's ongoing work is investigating the interactions between genetic deficiencies in antioxidant capacity and toxicant exposure in ovarian toxicity, reproductive aging and ovarian cancer.
Dr. Molloi received his PhD from the University of Wisconsin-Madison. At UCI, Dr. Molloi leads the Imaging Physics Laboratory. The lab focuses on the quantitative aspects of medical imaging and its applications for cardiovascular disease and breast cancer diagnosis.
Microbiology & Molecular Genetics
Dr. Tan received his MD from Johns Hopkins University. Dr. Tan is an Infectious Disease physician who is interested in how bacteria cause disease and developing novel antimicrobial approaches. He studies Chlamydia as a model system for a chronic bacterial infection, and also has a project examining the effect of antimicrobial peptides on intracellular chlamydiae.