Sharine Wittkopp Profile Page
Sharine Wittkopp


Bryn Mawr College
Major: Chemistry; Minor: Mathematics
Master's of Science, UC Irvine - Biochemistry.


Ralph Delfino
Gene expression responses to air pollution and modification by genetic variation
Michael Selsted
Vincent Procaccio
Douglas Wallace
Daniel Gillen, Michael Kleinman
Biochemistry, Epidemiology, Genetics, Toxicology
Environmental Toxicology
Newman, A.H.; Robarge, M. J.; Howard, I. M.; Wittkopp, S. L; Kopajtic, T.; Izenwasser, S. J.; Katz, J. L. Structure-Activity Relationships at the N-substituted-3a-[3’-Cl-, 4’-Cl- (4’, 4’’- diCl-substituted) diphenyl] methoxytropanes. J. Med. Chem. 2001, Vol. 44, No. 4, 633-640.

Suissa S, Wang Z, Poole J, Wittkopp S, Feder J, Shutt TE, Wallace DC, Shadel GS, Mishmar D. PLoS Genet. 2009 May;5(5), Ancient mtDNA genetic variants modulate mtDNA transcription and replication.. PLoS Genetics(2009), May; 5(5):e1000474.

Wittkopp S, Staimer N, Tjoa T, Gillen D, Daher N, Shafer M, Schauer JJ, Sioutas C, Delfino RJ. PLoS ONE 8(5): e64444. Mitochondrial Genetic Background Modifies the Relationship between Traffic-Related Air Pollution Exposure and Systemic Biomarkers of Inflammation.
S. Wittkopp, N. Staimer, T. Tjoa, D. Gillen, N. Daher, M. Shafer, J.J. Shauer, C. Sioutas, R. Delfino. Single nucleotide polymorphism -617 C/A in the Nrf2 gene promoter modifies gene expression-air pollution relationships in subjects with coronary artery disease. EHP. (Published Abstract)

S. Wittkopp, N. Staimer, T. Tjoa, D. Gillen, M. Shafer, JJ. Schauer, C. Sioutas, R.J. Delfino. Effect Modification Of Associations Between Air Pollution And Biomarkers Of Inflammation By Mitochondrial Haplogroup. American Thoracic Society 2012 International Conference, Published Abstract and Poster Discussion Presentation.

R.J. Delfino, N. Staimer, T. Tjoa, S Wittkopp, D. Gillen, M. Shafer, JJ. Schauer, C. Sioutas. Peripheral Blood Gene Expression and Traffic-related Air Pollution in Subjects with Coronary Artery Disease. American Thoracic Society 2012 International Conference, Published Abstract and Poster Presentation.

S. Wittkopp, S. Zaguri, Z. Wang, J. Poole, DC. Wallace, GS. Shadel, D. Mishmar. Ancient mtDNA Genetic Variants Modulate mtDNA Replication. UCI MSTP Retreat, 2008.

S. Wittkopp, S. Bannwarth, V. Paquis-Flucklinger, S. O’Hearn, A. Davila, P. Potluri, M. Simon, DC. Wallace, V. Procaccio. Identification and characterization of the novel mitochondrial DNA mutation 15952C>T in patient with neuromuscular phenotype. UCI MSTP Retreat, 2008.

Jennifer P. Gale, Sharine Wittkopp, Hu Li, David Tew, Thomas D. Meek, Sara H. Thrall, and Mehul P. Patel. Development of a Mechanism-Based High-Throughput Assay for Human Liver Glycogen Phosphorylase a for the Identification of Glucose-Sensitive Inhibitors. Society for Biomolecular Screening Conference 2005, Poster.


NRSA F30, National Institute of Environmental Health Sciences
UC Irvine/Stanley Behrens Public Impact Fellowship
American Thoracic Society, Assembly on Environmental and Occupational Health, Travel Award.
Women in Medicine, 2013 Student Scholarship for service to the LGBTQ community.
TEDxUCIrvine Salon Speaker, Feb. 19, 2013.

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