Alexander Lin Profile Page
Alexander Lin

Profile

Alexander
Lin
...
University of Nebraska, Lincoln
Biochemistry
2007

Research

Bruce Tromberg
Optical biomarkers of Alzheimer's disease
Steve Cramer
Devin Binder
Neuroscience, Bioengineering, Medical Imaging
1. Liu, G, Lin AJ, Tromberg BJ, Chen Z. A comparison of Doppler optical coherence tomography methods. Biomedical Optics Express. 2012; 3(10):2669-2680.

2. Koike MA, Lin AJ, Pham J, Nguyen E, Yeh JJ, Rahimian R, Tromberg BJ, Choi B, Green KN, Laferla FM. “APP Knockout Mice Experience Acute Mortality as the Result of Ischemia.” PLoS One. 2012;7(8):e42665. Epub 2012 Aug 9.

3. Lin AJ, Koike MA, Green KN, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ. “Spatial frequency domain imaging of intrinsic optical property contrast in a mouse model of Alzheimer's disease.” Ann Biomed Eng. 2011 Apr;39(4):1349-57. Epub 2011 Feb 19.

4. Weber JR, Cuccia DJ, Johnson WR, Bearman GH, Durkin AJ, Hsu M, Lin A, Binder DK, Wilson D, Tromberg BJ. “Multispectral imaging of tissue absorption and scattering using spatial frequency domain imaging and a computed-tomography imaging spectrometer.” J Biomed Opt. 2011 Jan-Feb;16(1):011015.

5. Zhu W, Lin A, Banerjee R. “Kinetic properties of polymorphic variants and pathogenic mutants in human cystathionine gamma-lyase”. Biochemistry. 2008 Jun 10;47(23):6226-32.

6. Prudova A, Albin M, Bauman Z, Lin A, Vitvitsky V, Banerjee R. “Testosterone regulation of homocysteine metabolism modulates redox status in human prostate cancer cells”. Antioxid Redox Signal. 2007 Nov;9(11):1875-81.
Oral Presentations:
1. “Importance of optical path length in determining brain hemodynamic properties in a pre-clinical mouse model of Alzheimer’s disease” Lin AJ, Ponticorvo A, Choi B, Durkin AJ, Tromberg BJ. Proceedings of Photonics West 2013 in San Francisco, CA. February 2-7, 2013.

2. “Determination of Near-Infrared Absorption spectrum of Iron-Nitrosyl Hemoglobin for potential in vivo detection”. Ganesan G, Warren R, Lin AJ, Cerussi A, Tromberg BJ, Galassetti P. American Diabetes Association 72nd Scientific Sessions, Philadelphia, Pennsylvania, June 8 – 12, 2012.

3. “Spatial frequency domain optical imaging of neurovascular coupling in a mouse model of Alzheimer's disease” Lin AJ, Konecky SD, Rice TB, Green KN, Tromberg BJ. Proceedings of Photonics West 2012 in San Francisco, CA. January 21-26, 2012.

4. “Development of coherent Spatial Frequency Domain Imaging (c-SFDI) for simultaneous determination of optical and dynamical properties of tissue”. Rice TB, Konecky SD, Mazhar A, Lin AJ, Durkin AJ, Choi B, Tromberg BJ. Proceedings of Photonics West 2012 in San Francisco, CA. January 21-26, 2012.

5. “Advances in optical tomography using spatial frequency domain imaging”. Konecky SD, Rice TB, Lin AJ, Mazhar A, Saager RB, Cuccia DJ, Durkin AJ, Choi B, Tromberg BJ. Proceedings of Photonics West 2012 in San Francisco, CA. January 21-26, 2012.

6. “Optical imaging techniques and neurovascular dysregulation in Alzheimer’s-related mouse models”. Lin AJ, Koike MA, Yeh JJ , Rahimian R , Pham JK, Nguyen E, LaFerla FM, Choi B, Green KN, Tromberg BJ. 15th annual UCI MSTP retreat at Lake Arrowhead 2010.

7. "Imaging and characterizing neurovascular reactivity with periodic gas inhalation challenges in a mouse model of Alzheimer’s disease". Lin AJ, Yeh JJ, Rahimian R, LaFerla FM, Tromberg BJ. Functional Near Infrared Spectroscopy Conference, Harvard 2010.

8. “Spatial frequency domain optical imaging of brain in an animal model of Alzheimer’s disease” Lin AJ, Koike MA, Green KN, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ. 11th Annual UC Systemwide Bioengineering Symposium, UC Davis 2010.

9. Undergraduate honors thesis defense “Kinetic Characterization of Mutant and Polymorphic Variants of Human Cystathionine-γ-lyase” University of Nebraska, Lincoln 2007

Posters
1. “Progression of vascular impairment in normal aging and 3xTg Alzheimer’s mouse model”. Lin AJ, Liu G, Castello NA, Yeh JJ, Rahimian R, Lee G, Tsay V, Durkin AJ, Choi B, LaFerla FM, Chen Z, Green KN, Tromberg BJ. Lasers in Medicine Gordon Conference 2012, Holderness, NH.

2. “Spatial frequency domain optical imaging of brain in an animal model of Alzheimer’s disease” Lin AJ, Koike MA, Green KN, Kim JG, Mazhar A, Rice TB, LaFerla FM, Tromberg BJ.. NIH NCCR/NIBIB P41 Director’s Meeting 2010.

3. “Optical detection of the pre-seizure state in vivo” Rajneesh KF, Lin AJ, Yeh JJ, Hsu MS, Binder DK. American Association of Neurological Surgeons (AANS) Annual Meeting 2010, Philadelphia, PA.

4. “Sushruta: Surgeon of ancient India” Rajneesh KF, Lin AJ, Tukaye DN, Yeh JJ, Hakimuddin H, Binder DK. American Association of Neurological Surgeons (AANS) Annual Meeting 2010, Philadelphia, PA.

5. “Towards in vivo multi-photon imaging of the pre-seizure state” Lin AJ, Krasieva T, Hsu M, Tromberg BJ, Binder DK (2nd place at Oct 23-25, 2009 14th annual MSTP retreat at Lake Arrowhead)

6. “Predicting Seizures with Near-Infrared Light” Lin AJ, Rajneesh KF, Yeh JJ, Hsu MS, Binder DK. (3rd place at Nov 21-23, 2008 13th annual MSTP retreat at Lake Arrowhead)

7. “Kinetic study of human cystathionine-γ-lyase” Lin AJ, Zhu W, Banerjee R (Feb 22-24, 2008 12th annual MSTP retreat at Lake Arrowhead)

Accolades

1. NIH/NIA F30 Ruth Kirschstein National Research Service Award (NRSA) : 7/11-7/15
2. American Society for Laser Surgery and Medicine student grant: 7/11-10/12
2007-09 Basic Science Certificate of Excellence from UCI School of Medicine

Alumni

Radiation-Oncology
Barnes Jewish Hospital
2015

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